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A Population Pharmacokinetic Model of High Dose Methotrexate in Adults with Cancer Identifies Baseline Albumin, Body Weight, and Time-dependent Creatinine as Predictors of Acute Kidney Injury

S. Howard, M. Ibarra,² R. Combs, and P. Schaiquevich

Clinical Characteristics and Infection-Related Outcomes in Patients with Lymphoid Malignancies with or without Secondary Immunodeficiencies: Results from a Retrospective Multi-Database Study

EVALUATING THE IMPACT OF THE COVID-19 PANDEMIC ON THE DIAGNOSIS AND STAGING OF NEW BREAST CANCER CASES: A RETROSPECTIVE ANALYSIS OF MEDICAL CHART DATA FROM THE UNITED STATES

Knapp R,1 Hardtstock F,1 Wilke T,2 Boner B,3 Hurmiz C,3 McCracken A3
1Cytel Inc., Berlin, Germany, 2IPAM e.V., Wismar, Germany, 3 Guardian Research Network, Spartanburg, SC, USA

 

Insights from a pharmacometric analysis of HDMTX in adults with cancer: clinically relevant covariates for application in precision dosing

Manuel Ibarra,Ryan Combs,Zachary L. Taylor,Laura B. Ramsey,Torben Mikkelsen,Randal K. Buddington,Jesper Heldrup,Jason N. Barreto,Martin Guscott,Jennifer Lowe,Charles Hurmiz,Suresh Marada,Scott C. Howard,Paula Schaiquevich

Leveraging the integrated EHR for trial matching across a nationwide network

Timothy Joseph Yeatman, Mark Watson, Adam Chasse